Anti-Hepatitis C Virus NS3 抗体 [24-8 ] (ab18662)


  • 製品名Anti-Hepatitis C Virus NS3 antibody [24-8 ]
    Hepatitis C Virus NS3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [24-8 ] to Hepatitis C Virus NS3
  • 特異性No cross reaction with HCV capsid region and other non-structural regions can be seen.
  • アプリケーション適用あり: WB, ELISAmore details
  • 免疫原

    A highly antigenic polypeptide consisting of essential sequences of at least 60 residues in length, which were selected from genes encoding the NS-3 region of Chinese HCV strains.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名24-8
  • ミエローマSp2/0-Ag14
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野


Our Abpromise guarantee covers the use of ab18662 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 4 µg/ml. Predicted molecular weight: 60 kDa. Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
    ab18662 will allow visualization of 200 ng/lane synthetic NS-3 protein.
  • ターゲット情報

    • 関連性HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins including NS3, and several non-structural proteins necessary for viral replication. The NS3 part of the polyprotein displays three enzymatic activities: serine protease, NTPase and RNA helicase. The NS3 serine proteinase (NS3P) is a non-structural hepatitis C protein responsible for proteolytic processing of other non-structural proteins; because of this, it is also the most extensively studied protein of the Hepatitis C genome. It is responsible for proteolytic processing of the entire downstream region of the HC polyprotein, catalyzing cleavage at the NS3/NS4a, NS4a/NS4b, NS4b/NS5a, and NS5a/NS5b sites to release the mature NS3, NS4a, NS4b, NS5a, and NS5b proteins.For proper function, NS3 requires NS4a as a cofactor, but, interestingly enough, NS3 also cleaves the NS4a protein. The molecular weight of the monomer NS3P is 70 kDa.
    • 細胞内局在Endoplasmic reticulum membrane
    • 別名
      • Hepatitis C Virus NS3 antibody
      • NS3 antibody
      • NS3P antibody
      • p70 antibody
      • Serine protease/NTPase/helicase antibody
      see all

    Anti-Hepatitis C Virus NS3 antibody [24-8 ] (ab18662) 使用論文

    ab18662 has not yet been referenced specifically in any publications.

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