製品の概要

  • 製品名Anti-Hepatitis C Virus E1 antibody
  • 製品の詳細
    Goat polyclonal to Hepatitis C Virus E1
  • アプリケーション適用あり: ELISA, WB, ICC/IFmore details
  • 種交差性
    交差種: Hepatitis C Virus
  • 免疫原

    Recombinant Hepatitis C Virus E1 (genotype 1a).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 精製度Ion Exchange Chromatography
  • 特記事項(精製)ab110972 is >95% pure by Sodium sulfate precipitation and ion exchange chromatography.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution. Reacts with genotype 1a.
WB Use at an assay dependent dilution. Predicted molecular weight: 23 kDa. Reacts with genotypes 1b and 2a.
ICC/IF Use at an assay dependent dilution. Reacts with genotype 1b, but does not react with genotype 2a.

ターゲット情報

  • 関連性Envelope glycoproteins E1 and E2 are involved in virus attachment to the host cell as well as in virus endocytosis and fusion with host membrane. E2 inhibits human EIF2AK2/PKR activation, preventing the establishment of an antiviral state. E2 is a viral ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on liver sinusoidal endothelial cells and macrophage-like cells of lymph node sinuses. These interactions allow capture of circulating HCV particles by these cells and subsequent transmission to permissive cells.
  • 参照データベース
    • 別名
      • E1 envelope glycoprotein antibody
      • HCV envelope glycoprotein antibody
      • Hepatitis C Virus envelope glycoprotein antibody

    Anti-Hepatitis C Virus E1 antibody (ab110972) 使用論文

    ab110972 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab110972.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"