Anti-Hepatitis C Virus Core NS3 + NS4 抗体 (ab20324)

製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 特記事項(精製)>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab20324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Conjugation
ELISA
  • 追加情報Conjugation: Use at an assay dependent dilution.
    ELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性HCV is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR. The NS3 serine proteinase (NS3P) is a non-structural hepatitis C protein responsible for proteolytic processing of other non-structural proteins; because of this, it is also the most extensively studied protein of the Hepatitis C genome.
    • 細胞内局在Endoplasmic reticulum and Mitochondrial
    • 別名
      • helicase NS3 antibody
      • Non structural protein 4A antibody
      • Non structural protein 4B antibody
      • NS3P antibody
      • NS4A antibody
      • NS4B antibody
      • NTPase antibody
      • p27 antibody
      • p70 antibody
      • p8 antibody
      • Serine protease antibody
      see all

    Anti-Hepatitis C Virus Core NS3 + NS4 antibody (ab20324) 使用論文

    ab20324 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your patience. I now have the amino acid numbers used as the immunogen for ab20324. Immunogen aa sequences are: core #1-#142 NS3 #1252-#1477 NS4 #1689- #1735 I hope that this information is helpful to you. Please do n...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"