製品の概要

  • 製品名Anti-Hepatitis C Virus antibody [NS5B-6] (FITC)
    Hepatitis C Virus 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [NS5B-6] to Hepatitis C Virus (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性Specific to Human HCV NS5b protein of genotype 1b. Not tested in other genotypes.
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Hepatitis C Virus
  • 免疫原

    A region of NS5b protein of Hepatitis C Virus genotype 1b expressed in E. coli.

  • ポジティブ・コントロール
    • Chimp liver cells and cell lysate, infected with recombinant vaccinia virus containing a HCV genome cDNA.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーConstituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • 精製度>90% by SDS-PAGE
  • 特記事項(精製)ab122979 is filter-sterilized.
  • ポリ/モノモノクローナル
  • クローン名NS5B-6
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 327 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 関連性Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
  • 細胞内局在Virus surface
  • 参照データベース
    • 別名
      • Genome polyprotein antibody
      • HCV antibody
      • Hepatitis C virus polyprotein antibody

    Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) 画像

    • Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) (ab122979) + Chimp liver cell lysate, infected with recombinant vaccinia virus containing a HCV genome cDNA

      Predicted band size : 327 kDa
      Observed band size : 58 kDa (why is the actual band size different from the predicted?)
    • ab122979, staining Hepatitis C Virus NS5b protein in Acetone-fixed Chimp liver cells infected with recombinant vaccinia virus containing a HCV genome cDNA by Immunofluorescence.

    Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) (ab122979) 使用論文

    This product has been referenced in:
    • Manabe S  et al. Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3. Virology 198:636-44 (1994). Read more (PubMed: 8291245) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"