Anti-Hepatitis B Virus Surface Antigen (Ayw) 抗体 [HB5] (ab20724)

製品の概要

  • 製品名
    Anti-Hepatitis B Virus Surface Antigen (Ayw) antibody [HB5]
  • 製品の詳細
    Mouse monoclonal [HB5] to Hepatitis B Virus Surface Antigen (Ayw)
  • 特異性
    Hepatitis B virus surface antigen. Reacts with the following HBsAg subtypes: ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-, ayw3 (Fer).
  • アプリケーション
    適用あり: ELISAmore details
  • 免疫原

    Recombinant HBsAg of ayw subtype.

  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab20724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報
    ELISA: Detection of HBsAg in two-site enzyme immunoassay. Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
    • 細胞内局在
      Cytoplasmic
    • 別名
      • HBsAg antibody

    参考文献

    ab20724 has not yet been referenced specifically in any publications.

    レビューと Q&A

    Thank you for your email.
    We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
    If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet ...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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