Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) 抗体 (FITC) (ab32914)

製品の概要

  • 製品名Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (FITC)
    Hepatitis B Virus Surface Antigen (Ad/Ay) 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Hepatitis B Virus Surface Antigen (Ad/Ay) (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性This antibody recognizes Hepatitis B Surface Antigen, subtypes ad and ay.
  • アプリケーション適用あり: ELISA, ICC/IFmore details
  • 種交差性
    Reacts vith human Hepatitis B virus
  • 免疫原

    Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad and ay.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
ICC/IF
  • 追加情報ELISA: 1/10000.
    IF: 1/10 - 1/50. Acetone fixation of the antigen source is recommended prior to staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
    • 細胞内局在Virion membrane
    • 別名
      • HBsAg antibody
      • HBV major surface antigen antibody
      • HBV surface antigen antibody
      • Hepatitis B Virus major surface antigen antibody
      • Major surface antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (FITC) (ab32914) 使用論文

    This product has been referenced in:
    • Deng Q  et al. Hepatitis B virus as a gene delivery vector activating foreign antigenic T cell response that abrogates viral expression in mouse models. Hepatology 50:1380-91 (2009). Read more (PubMed: 19821533) »
    • Deng Q  et al. Identification and characterization of peptides that interact with hepatitis B virus via the putative receptor binding site. J Virol 81:4244-54 (2007). Read more (PubMed: 17192308) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"