Anti-Hepatitis B Virus Surface Antigen ad + ay 抗体 [HB24] (ab54247)

製品の概要

  • 製品名Anti-Hepatitis B Virus Surface Antigen ad + ay antibody [HB24]
    Hepatitis B Virus Surface Antigen ad + ay 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [HB24] to Hepatitis B Virus Surface Antigen ad + ay
  • 特異性ab54247 recognises a common epitope of the plasma HBsAg of ad and ay subtypes.
  • アプリケーション適用あり: ELISAmore details
  • 種交差性
    交差種: Hepatitis B virus
  • 免疫原

    Full length native protein (purified) (Hepatitis B virus)

  • 特記事項Affinity 1.4 x 10-9 M (ad) 2.0 x 10-9 M (ay)

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名HB24
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab54247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
  • 細胞内局在Secreted
  • 参照データベース
    • 別名
      • HBsAg antibody
      • HBV major surface antigen antibody
      • HBV surface antigen antibody
      • Hepatitis B Virus major surface antigen antibody
      • Major surface antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus Surface Antigen ad + ay antibody [HB24] (ab54247) 使用論文

    ab54247 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"