Anti-Hepatitis B Virus pre S2 Antigen 抗体 [S9] (ab65406)

製品の概要

  • 製品名Anti-Hepatitis B Virus pre S2 Antigen antibody [S9]
    Hepatitis B Virus pre S2 Antigen 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [S9] to Hepatitis B Virus pre S2 Antigen
  • 特異性Reacts strongly with WHc but not DHBc in ELISA and Western blot. Also reacts with synthetic HBc peptides.
  • アプリケーション適用あり: IHC-P, IHC-Fr, WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Hepatitis B virus
  • 免疫原

    Recombinant full length HBcAg (ayw type)

  • エピトープamino acids 130-138 of preS2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.01% Sodium Azide
    Constituents: 10mM PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノモノクローナル
  • クローン名S9
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab65406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 関連性The human hepatitis B virus (HBV) is a DNA virus that causes chronic infections that frequently lead to the development of cirrhosis and cellular hepatocellular carcinoma. The HBsAg (surface antigen) gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. Because of the multiple start codons, polypeptides of three different sizes called large, middle, and small (pre-S1 + pre-S2 + S, pre-S2 + S, or S) are produced. The preS2 domain is the minimal functional unit of transcription activators that are encoded by the Hepatitis B virus (HBV) surface (S) gene. It is present in more than one-third of the HBV-integrates in HBV induced hepatocarcinoma (HCC). Pre-S2 is a diagnostically important surface antigen of human hepatitis B virus. The PreS domain (S1 + S2) of Hepatitis B virus (HBV) surface antigen may be a good candidate for an effective vaccine as it activates both B and T cells besides binding to hepatocytes.
  • 細胞内局在Virion membrane (By similarity).
  • 参照データベース
    • 別名
      • HBV pre S2 Antigen antibody
      • HBV pre S2 protein antibody
      • Hepatitis B Virus pre S2 protein antibody
      • PreS2/S antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus pre S2 Antigen antibody [S9] (ab65406) 使用論文

    ab65406 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. The epitope recognized by ab65406 has been mapped to amino acids 130-138 of HBV preS2: MCLRRFIIF. I hope this helps, please let me know if you need any additional information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"