Anti-Hemagglutinin 抗体 [16B12] (DyLight® 488) (ab117488)

製品の概要

  • 製品名
    Anti-Hemagglutinin antibody [16B12] (DyLight® 488)
    Hemagglutinin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [16B12] to Hemagglutinin (DyLight® 488)
  • 標識
    DyLight® 488. Ex: 493nm, Em: 518nm
  • アプリケーション
    適用あり: ICC/IF, Flow Cytmore details
  • 免疫原

    The influenza hemagglutinin epitope (YPYDVPDYA).

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 1.42% Sodium phosphate, 0.88% Sodium chloride, 1% BSA
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    16B12
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500 - 1/5000.
Flow Cyt Use at an assay dependent concentration.

ターゲット情報

  • 関連性
    Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
  • 細胞内局在
    Cell membrane; apical cell membrane; single-pass type I membrane protein.
  • 別名
    • HA antibody
    • HA1 antibody
    • HA2 antibody
    • Hemagglutinin antibody

画像

  • ab117488 staining Hemagglutinin in Monkey cos7 cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde. Samples were incubated with primary antibody (1/100) for 1 hour at 22°C.

    See Abreview

参考文献

ab117488 has not yet been referenced specifically in any publications.

レビューと Q&A

Application
Immunocytochemistry/ Immunofluorescence
Sample
Monkey Cell (cos7)
Specification
cos7
Permeabilization
No
Fixative
Formaldehyde
Username

Ms. Ya Zhou

Verified customer

投稿 Dec 13 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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