The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Hellebrin is a plant cardiac glycoside which has a bufadienolide-steroid structure. It is an extremely potent inhibitor of the Na+/K+-ATPase (sodium pump) blocking the active efflux of Na ions and reuptake of K ions by this membrane enzyme.
Hellebrin is a strong immunosuppressor inhibiting T cell activity with much higher potency than cortisol or cyclosporin A. Hellebrin induces caspase-dependent apoptosis and may have anti-tumour properties.
Hellebrigenin glucorhamnoside antibody
has not yet been referenced specifically in any publications.