製品の概要

  • 製品名Anti-Helicobacter pylori CagA antibody [B818M]
  • 製品の詳細
    Mouse monoclonal [B818M] to Helicobacter pylori CagA
  • アプリケーション適用あり: WB, ELISA, Sandwich ELISAmore details
  • 種交差性
    Reacts with
  • 免疫原

    Recombinant fragments of CA gene of Helicobacter pylori.

  • エピトープab90490 recognizes an epitope localized between Asp562 and Gln795 in the GenBank FJ428215 amino acid sequence.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)ab90490 is purified from ascites by Protein G chromatography and is >95% pure as assessed by SDS-PAGE.
  • ポリ/モノモノクローナル
  • クローン名B818M
  • ミエローマSp2/0
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab90490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 124 kDa.
ELISA Use at an assay dependent concentration.
Sandwich ELISA Use at an assay dependent concentration. This antibody has been tested as the capture antibody, while the recommended pair was used as detection antibody.

ターゲット情報

  • 関連性It is known that H. pylori strains exhibit a significant degree of diversity. The great variability in the H. pylori genome may explain why not all infected individuals suffer from ulcer. Some H. pylori strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant.
  • 別名
    • 120 kDa protein antibody
    • CAG pathogenicity island protein 26 antibody
    • cag26 antibody
    • cagA antibody
    • cai antibody
    • Cytotoxicity-associated immunodominant antigen antibody
    • H. pylori CagA antibody
    • H. pylori cytokine associated gene A antibody
    • Helicobacter pylori cytokine associated gene A antibody
    see all

Anti-Helicobacter pylori CagA antibody [B818M] (ab90490) 使用論文

This product has been referenced in:
  • McCracken KW  et al. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516:400-4 (2014). Read more (PubMed: 25363776) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"