Anti-HEC1/HEC 抗体 [EPR5342] (ab109496)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR5342] to HEC1/HEC
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-HEC1/HEC antibody [EPR5342]
HEC1/HEC 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR5342] to HEC1/HEC -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF or IHC-P -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- Jurkat, HeLa, NCCIT, and Human spleen lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR5342 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109496の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/10000 - 1/50000. Predicted molecular weight: 74 kDa.
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特記事項 |
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WB
1/10000 - 1/50000. Predicted molecular weight: 74 kDa. |
ターゲット情報
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機能
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. -
配列類似性
Belongs to the NDC80/HEC1 family. -
発生段階
Expression peaks in mitosis. -
翻訳後修飾
Phosphorylation begins in S phase of the cell cycle and peaks in mitosis. Phosphorylated by NEK2. May also be phosphorylated by AURKA and AURKB. -
細胞内局在
Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. - Information by UniProt
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参照データベース
- Entrez Gene: 10403 Human
- Entrez Gene: 67052 Mouse
- Entrez Gene: 301701 Rat
- Omim: 607272 Human
- SwissProt: O14777 Human
- SwissProt: Q9D0F1 Mouse
- Unigene: 414407 Human
- Unigene: 225956 Mouse
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別名
- from Entrez Gene ; antibody
- HEC antibody
- Highly expressed in cancer antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab109496 は論文での使用が確認できていません。