製品の概要

  • 製品名Anti-HDAC3 antibody
    HDAC3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HDAC3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chicken
  • 免疫原

    Synthetic peptide:

    KTVAYFYDPDVGNFH

    , corresponding to amino acids 2-17 of Human HDAC3.

  • ポジティブ・コントロール
    • Hela whole cell extract.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab11967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 50 kDa.

ターゲット情報

  • 機能Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
  • 組織特異性Widely expressed.
  • 配列類似性Belongs to the histone deacetylase family. HD type 1 subfamily.
  • 翻訳後修飾Sumoylated in vitro.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HD3 antibody
    • HDAC 3 antibody
    • HDAC3 antibody
    • HDAC3_HUMAN antibody
    • Histone deacetylase 3 antibody
    • RPD3 2 antibody
    • RPD3 antibody
    • RPD3-2 antibody
    • SMAP45 antibody
    see all

Anti-HDAC3 antibody 画像

  • HDAC3 detection by Western blot. The analysis of HDAC3 in HeLa cell extract with anti-HDAC3 pAb. A protein band of approximate molecular weight of 50 kDa was detected.

Anti-HDAC3 antibody (ab11967) 使用論文

ab11967 has not yet been referenced specifically in any publications.

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I am very pleased to hear you would like to accept our offer and test ab11967 on rat samples. This code will give you one free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for rat and include this code in...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"