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ab7029 は 58 報の論文で使用されています。

  • Muralidharan B  et al. LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11. J Neurosci 37:194-203 (2017). IP, CHIPseq ; Mouse . PubMed: 28053041
  • Tsukamoto D  et al. HNF-4 participates in the hibernation-associated transcriptional regulation of the chipmunk hibernation-related protein gene. Sci Rep 7:44279 (2017). ChIP . PubMed: 28281641
  • Romani B  et al. HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin. Sci Rep 6:31924 (2016). PubMed: 27550312
  • Romani B  et al. HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages. J Biol Chem 291:2696-711 (2016). WB, IP ; Human . PubMed: 26679995
  • Lakisic G  et al. Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism. PLoS Genet 12:e1005898 (2016). PubMed: 26938916
  • Contreras PS  et al. Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway. Biochim Biophys Acta 1859:269-79 (2016). PubMed: 26603102
  • Mahgoub M  et al. MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors. Nat Neurosci 19:1506-1512 (2016). PubMed: 27668390
  • Yamashita D  et al. Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2a. J Biol Chem 291:11619-34 (2016). PubMed: 27068747
  • Hua G  et al. Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex. Proc Natl Acad Sci U S A 113:E635-43 (2016). PubMed: 26712006
  • Hua G  et al. GR SUMOylation and formation of an SUMO-SMRT/NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression. Proc Natl Acad Sci U S A 113:E626-34 (2016). PubMed: 26712002
  • Akiyama T  et al. Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells. DNA Res 22:307-18 (2015). PubMed: 26324425
  • Soragni E  et al. Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia. Front Neurol 6:44 (2015). WB ; Human . PubMed: 25798128
  • Xiao X  et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun 6:8266 (2015). WB ; Mouse . PubMed: 26365427
  • Matthews GM  et al. Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies. Blood 126:2392-403 (2015). WB ; Mouse . PubMed: 26447190
  • Mould AW  et al. Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation. PLoS Genet 11:e1005375 (2015). WB . PubMed: 26158850
  • Heckman LD  et al. Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice. Elife 3:N/A (2014). WB ; Mouse . PubMed: 24970834
  • Shen W  et al. Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated Fatty acids. Sci Rep 4:5282 (2014). ChIP ; Mouse . PubMed: 24923522
  • Urvalek AM & Gudas LJ Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells. J Biol Chem 289:19519-30 (2014). ChIP ; Human . PubMed: 24821725
  • Petchey LK  et al. Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy. Proc Natl Acad Sci U S A 111:9515-20 (2014). IP ; Mouse . PubMed: 24938781
  • Bowman CJ  et al. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. Nat Cell Biol 16:1202-14 (2014). PubMed: 25402684
  • Ptasinska A  et al. Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal. Cell Rep 8:1974-1988 (2014). WB . PubMed: 25242324
  • Wang Y  et al. Class I HDAC imaging using [ (3)H]CI-994 autoradiography. Epigenetics 8:756-64 (2013). PubMed: 23803584
  • Santoro F  et al. A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. Blood 121:3459-68 (2013). PubMed: 23440245
  • Ouyang H  et al. Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription. PLoS One 8:e62192 (2013). ChIP . PubMed: 23626788
  • Ramamoorthy S & Cidlowski JA Ligand-induced repression of the glucocorticoid receptor gene is mediated by an NCoR1 repression complex formed by long-range chromatin interactions with intragenic glucocorticoid response elements. Mol Cell Biol 33:1711-22 (2013). PubMed: 23428870
  • Ling T  et al. CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5. Biochem Biophys Res Commun 437:101-7 (2013). PubMed: 23796711
  • Frumm SM  et al. Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. Chem Biol 20:713-25 (2013). WB ; Human . PubMed: 23706636
  • Mannava S  et al. KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells. Blood 119:1450-8 (2012). PubMed: 22144178
  • Wu M  et al. Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation. J Neurosci 32:6651-64 (2012). PubMed: 22573687
  • Whyte WA  et al. Enhancer decommissioning by LSD1 during embryonic stem cell differentiation. Nature 482:221-5 (2012). PubMed: 22297846
  • Lin YY  et al. Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature 482:251-5 (2012). PubMed: 22318606
  • Chakravarthy H  et al. Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery. FASEB J 25:206-18 (2011). ChIP . PubMed: 20876214
  • Arzenani MK  et al. Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics. Mol Cell Biol 31:4119-28 (2011). PubMed: 21791605
  • Chen S  et al. Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation. J Biol Chem 286:32775-89 (2011). PubMed: 21778236
  • Cox JL  et al. Banf1 is required to maintain the self-renewal of both mouse and human embryonic stem cells. J Cell Sci 124:2654-65 (2011). WB . PubMed: 21750191
  • Potts RC  et al. CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS One 6:e24515 (2011). WB . PubMed: 21931736
  • Su RC  et al. Epigenetic control of IRF1 responses in HIV-exposed seronegative versus HIV-susceptible individuals. Blood 117:2649-57 (2011). ChIP ; Human . PubMed: 21200019
  • Fisher KW  et al. Kinase Suppressor of Ras 1 (KSR1) Regulates PGC1{alpha} and Estrogen-Related Receptor {alpha} To Promote Oncogenic Ras-Dependent Anchorage-Independent Growth. Mol Cell Biol 31:2453-61 (2011). PubMed: 21518958
  • Swiss VA  et al. Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation. PLoS One 6:e18088 (2011). PubMed: 21490970
  • Golding MC  et al. Multiple epigenetic modifiers induce aggressive viral extinction in extraembryonic endoderm stem cells. Cell Stem Cell 6:457-67 (2010). ChIP . PubMed: 20452320
  • Hang CT  et al. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466:62-7 (2010). WB, IHC-P ; Mouse . PubMed: 20596014
  • Cox JL  et al. Sox2 uses multiple domains to associate with proteins present in Sox2-protein complexes. PLoS One 5:e15486 (2010). PubMed: 21103394
  • Powell ML  et al. NCoR1 mediates papillomavirus E8;E2C transcriptional repression. J Virol 84:4451-60 (2010). PubMed: 20181716
  • Baltus GA  et al. A positive regulatory role for the mSin3A-HDAC complex in pluripotency through Nanog and Sox2. J Biol Chem 284:6998-7006 (2009). ChIP ; Mouse . PubMed: 19139101
  • Tyson-Capper AJ  et al. Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors. J Mol Endocrinol 43:29-41 (2009). PubMed: 19339282
  • Xu C  et al. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol 16:980-9 (2009). WB ; Human . PubMed: 19778726
  • Ahmed S  et al. Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress. J Cell Sci 121:1046-53 (2008). WB ; Human . PubMed: 18334557
  • Vincent A  et al. Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases. FASEB J : (2008). PubMed: 18492726
  • Gomez-Duran A  et al. Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner. J Mol Biol 380:1-16 (2008). ChIP ; Mouse . PubMed: 18508077
  • Montgomery RL  et al. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes Dev 21:1790-802 (2007). WB, ICC/IF, ChIP ; Mouse, Rat . PubMed: 17639084
  • Senese S  et al. Role for histone deacetylase 1 in human tumor cell proliferation. Mol Cell Biol 27:4784-95 (2007). WB ; Human . PubMed: 17470557
  • Ropero S  et al. A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat Genet 38:566-9 (2006). PubMed: 16642021
  • Yang SH & Sharrocks AD PIASxalpha differentially regulates the amplitudes of transcriptional responses following activation of the ERK and p38 MAPK pathways. Mol Cell 22:477-87 (2006). PubMed: 16713578
  • Alao JP  et al. Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells. Mol Cancer 5:40 (2006). PubMed: 17018141
  • Yang SH  et al. An extended consensus motif enhances the specificity of substrate modification by SUMO. EMBO J 25:5083-93 (2006). PubMed: 17036045
  • Kuo HY  et al. SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx. Proc Natl Acad Sci U S A 102:16973-8 (2005). ChIP ; Human . PubMed: 16287980
  • Phillips RJ  et al. Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: involvement of specificity protein-1 (Sp1), Sp3, Sp4, Sp-like proteins, and histone deacetylases. J Clin Endocrinol Metab 90:3479-90 (2005). PubMed: 15788387
  • Yang SH & Sharrocks AD SUMO promotes HDAC-mediated transcriptional repression. Mol Cell 13:611-7 (2004). PubMed: 14992729

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