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RabMAb

Anti-HDAC10 抗体 [EPR3576] (ab108934)

製品の概要

  • 製品名
    Anti-HDAC10 antibody [EPR3576]
    HDAC10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3576] to HDAC10
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, IP, ICCmore details
    適用なし: Flow Cyt or IHC-P
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide within Human HDAC10 aa 350-450. The exact sequence is proprietary.

  • ポジティブ・コントロール
    • HeLa, 293T, Jurkat, HepG2, A673 and NIH/3T3 cell lysates
  • 特記事項

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 75 kDa.
IP 1/10 - 1/100.
ICC 1/100 - 1/250.
  • 追加情報
    Is unsuitable for Flow Cyt or IHC-P.
  • ターゲット情報

    • 機能
      Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • 組織特異性
      Ubiquitous. High expression in liver, spleen, pancreas and kidney.
    • 配列類似性
      Belongs to the histone deacetylase family. HD type 2 subfamily.
    • 細胞内局在
      Cytoplasm. Nucleus. Excluded from the nucleoli.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZP761B039 antibody
      • HD 10 antibody
      • HD10 antibody
      • HDA10_HUMAN antibody
      • HDAC 10 antibody
      • Hdac10 antibody
      • Histone deacetylase 10 antibody
      • MGC149722 antibody
      • OTTHUMP00000028555 antibody
      see all

    画像

    • All lanes : Anti-HDAC10 antibody [EPR3576] (ab108934) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : HepG2 cell lysate
      Lane 5 : A673 cell lysate
      Lane 6 : NIH/3T3 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 75 kDa

    参考文献

    This product has been referenced in:
    • Mondello P  et al. Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265 mutations. JCI Insight 2:e90196 (2017). WB ; Human . Read more (PubMed: 28352655) »

    See 1 Publication for this product

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab108934.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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