製品の概要

  • 製品名Anti-HDAC10 antibody
    HDAC10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HDAC10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids near the N terminus of Human HDAC10.

  • ポジティブ・コントロール
    • Jurkat Cells, Mouse Intestine and Rat Brain for Western blot.

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab18971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1 - 4 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 71 kDa). A 55 kDa band can also be detected in mouse and rat tissue lysate.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • 組織特異性Ubiquitous. High expression in liver, spleen, pancreas and kidney.
    • 配列類似性Belongs to the histone deacetylase family. HD type 2 subfamily.
    • 細胞内局在Cytoplasm. Nucleus. Excluded from the nucleoli.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZP761B039 antibody
      • HD 10 antibody
      • HD10 antibody
      • HDA10_HUMAN antibody
      • HDAC 10 antibody
      • Hdac10 antibody
      • Histone deacetylase 10 antibody
      • MGC149722 antibody
      • OTTHUMP00000028555 antibody
      see all

    Anti-HDAC10 antibody 画像

    • All lanes : Anti-HDAC10 antibody (ab18971) at 2.5 µg/ml

      Lane 1 : Jurkat cell lysate (30ug)
      Lane 2 : Mouse intestine lysate (30ug)
      Lane 3 : Rat brain lysate (30ug)


      Predicted band size : 71 kDa
      Observed band size : 74 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.

    Anti-HDAC10 antibody (ab18971) 使用論文

    This product has been referenced in:
    • Liu J  et al. Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells. J Transl Med 14:7 (2016). Human . Read more (PubMed: 26747087) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab18971.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"