製品の概要

  • 製品名Anti-Hck antibody
    Hck 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Hck
  • アプリケーション適用あり: ICC/IF, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthesized non-phosphopeptide derived from human Hck around the phosphorylation site of tyrosine 410.

  • ポジティブ・コントロール
    • HepG2 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500 - 1/1000.
ELISA 1/5000.

ターゲット情報

  • 機能May serve as part of a signaling pathway coupling the Fc receptor to the activation of the respiratory burst. May also contribute to neutrophil migration and may regulate the degranulation process of neutrophils.
  • 組織特異性Expressed predominantly in cells of the myeloid and B-lymphoid lineages.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • ドメインThe SH3 domain mediates binding to HIV-1 Nef.
  • 細胞内局在Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane > caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3.
  • Information by UniProt
  • 参照データベース
  • 製品の状態This protein is known to be similar in amino acid sequence to LCK (P06239), FYN (P06241), YES1 (P07947), SRC (P12931), and LYN (P07948). Therefore, cross-reactivity with these homologous proteins may be observed. We would be happy to provide immunogen alignment information upon request.
  • 別名
    • Bmk antibody
    • Hck 1 antibody
    • Hck antibody
    • HCK_HUMAN antibody
    • Hemopoietic cell kinase antibody
    • JTK9 antibody
    • p59-HCK/p60-HCK antibody
    • p59Hck antibody
    • p59HCK/p60HCK antibody
    • p61Hck antibody
    • Tyrosine protein kinase HCK antibody
    • Tyrosine-protein kinase HCK antibody
    see all

Anti-Hck antibody 画像

  • Immunofluorescence analysis of Hck expression in HepG2 cells, using ab63352 at 1/500. Left: untreated cells. Right: cells treated with immunising peptide.

Anti-Hck antibody (ab63352) 使用論文

ab63352 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab63352.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"