製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to HBXIP
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human) with tag.

  • ポジティブ・コントロール
    • Full length recombinant HBXIP with tag.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab66258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    ELISA: Use at an assay dependent dilution.
    WB: 1/1000 - 1/2500. Predicted molecular weight: 10 kDa.

    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
    • 組織特異性
      Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
    • 配列類似性
      Belongs to the HBXIP family.
    • 翻訳後修飾
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HBV X interacting protein antibody
      • HBV X-interacting protein antibody
      • HBX interacting protein antibody
      • HBX-interacting protein antibody
      • hbxip antibody
      • HBXIP_HUMAN antibody
      • Hepatitis B virus X interacting protein antibody
      • Hepatitis B virus X-interacting protein antibody
      • LAMTOR5 antibody
      • Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody
      • MGC71071 antibody
      • Ragulator complex protein LAMTOR5 antibody
      • XIP antibody
      see all

    画像



    • Predicted band size : 10 kDa

    プロトコール

    参考文献

    ab66258 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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