Anti-HB9/HLXB9/MNX1 抗体 (ab92606)
Key features and details
- Rabbit polyclonal to HB9/HLXB9/MNX1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-HB9/HLXB9/MNX1 antibody
HB9/HLXB9/MNX1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HB9/HLXB9/MNX1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Dog -
免疫原
Synthetic peptide corresponding to Mouse HB9/HLXB9/MNX1 aa 330-380.
Database link: NP_064328.2 -
ポジティブ・コントロール
- WB: MOLT 4 cell lysate; IHC-P: Mouse pancreas tissue.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92606の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 41 kDa.
|
|
IHC-P |
Use a concentration of 5 µg/ml.
|
特記事項 |
---|
WB
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 41 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
-
機能
Putative transcription factor involved in pancreas development and function. -
組織特異性
Expressed in lymphoid and pancreatic tissues. -
関連疾患
Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. -
配列類似性
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 3110 Human
- Entrez Gene: 15285 Mouse
- Omim: 142994 Human
- SwissProt: P50219 Human
- SwissProt: Q9QZW9 Mouse
- Unigene: 37035 Human
- Unigene: 103760 Mouse
-
別名
- HB 9 antibody
- HB9 antibody
- HLXB 9 antibody
see all
画像
-
Immunohistochemistry analysis of HB9/HLXB9/MNX1 expression in formalin-fixed, paraffin-embedded Mouse pancreas tissue using: an isotype control (1) or ab92606 at 5µg/ml (2 and 3).
-
All lanes : Anti-HB9/HLXB9/MNX1 antibody (ab92606) at 0.5 µg/ml
Lane 1 : MOLT 4 cell lysate
Lane 2 : MOLT 4 cell lysate with immunizing peptide
Secondary
All lanes : HRP-conjugated Goat anti-Rabbit IgG
Predicted band size: 41 kDa
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (6)
ab92606 は 6 報の論文で使用されています。
- Miralles MP et al. Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons. Front Cell Neurosci 16:1054270 (2022). PubMed: 36619669
- Sansa A et al. Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons. Neurobiol Dis 155:105366 (2021). PubMed: 33845129
- Sansa A et al. Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons. Acta Neuropathol Commun 9:122 (2021). PubMed: 34217376
- de la Fuente S et al. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models. Cell Death Dis 11:487 (2020). PubMed: 32587237
- Cosset É et al. Modeling Poliovirus Infection Using Human Engineered Neural Tissue Enriched With Motor Neuron Derived From Embryonic Stem Cells. Front Cell Dev Biol 8:593106 (2020). PubMed: 33490061
- Osaki T et al. On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease. Nat Protoc 15:421-449 (2020). PubMed: 31932771