特異性The antibody is specific for HB9 in Human and Mouse. This has been confirmed by Immunohistochemical analysis of Normal Term and First Trimester Human Placenta as well as western blot analysis of mouse Neuroblastoma and Spinal Cord cells (NSC-34).
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
1/200 - 1/2600.
1/400. Predicted molecular weight: 41 kDa.
機能Putative transcription factor involved in pancreas development and function.
組織特異性Expressed in lymphoid and pancreatic tissues.
関連疾患Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.