製品の概要

  • 製品名Anti-Haptoglobin antibody
    Haptoglobin 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Haptoglobin
  • 特異性This antibody recognizes haptoglobin. It is monospecific by IEP against human serum and plasma.
  • 種交差性
    交差種: Human
  • 免疫原

    Affinity purified human haptoglobin.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: Tris buffered saline
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab31205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
AP
  • 追加情報Suitable for use in Turbidimetric or Nephelometric assay. Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
      Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
    • 組織特異性Expressed by the liver and secreted in plasma.
    • 関連疾患Anhaptoglobinemia
    • 配列類似性Belongs to the peptidase S1 family.
      Contains 1 peptidase S1 domain.
      Contains 2 Sushi (CCP/SCR) domains.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Binding peptide antibody
      • BP antibody
      • Haptoglobin alpha chain antibody
      • Haptoglobin alpha(1S) beta antibody
      • Haptoglobin alpha(2FS) beta antibody
      • Haptoglobin beta chain antibody
      • Haptoglobin, alpha polypeptide antibody
      • Haptoglobin, beta polypeptide antibody
      • HP antibody
      • HP2 ALPHA2 antibody
      • HP2ALPHA2 antibody
      • HPA1S antibody
      • HPT antibody
      • HPT_HUMAN antibody
      • MGC111141 antibody
      • Zonulin antibody
      see all

    Anti-Haptoglobin antibody (ab31205) 使用論文

    ab31205 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab31205.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"