Anti-Hantavirus nucleocapsid protein 抗体 [5E11] (ab34759)

製品の概要

  • 製品名
    Anti-Hantavirus nucleocapsid protein antibody [5E11]
    Hantavirus nucleocapsid protein 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [5E11] to Hantavirus nucleocapsid protein
  • 特異性
    This antibody reacts with nucleocapsid proteins of Puumala hantaviruses: Vranica, Sotkamo and Kazan and reacts with hantavirus-infected cells. It cross-reacts with nucleocapsid proteins of Andes, Sin Nombre and Seoul hantaviruses. It does not cross-react with hamster polyomavirus major capsid protein VP1, nor with nucleocapsid proteins of measles and mumps viruses.
  • アプリケーション
    適用あり: ICC/IFmore details
  • 種交差性
    Reacts with hantavirus. Not yet tested in other species.
  • 免疫原

    Recombinant fragment -recombinant chimeric protein harbouring N-terminal segment (1-120 aa) of Puumala hantavirus (strain Vranica-Hällnäs) nucleocapsid protein, expressed in yeast S.cerevisiae.

  • エピトープ
    The epitope recognized by this antibody is localized at the N-terminus, between amino acids 1 and 45 of hantavirus nucleocapsid protein.
  • 特記事項

    This product was changed from ascites to tissue culture supernatant on 28/11/2017. Please note that the dilutions may need to be adjusted accordingly.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: Tissue culture supernatant
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    5E11
  • ミエローマ
    Sp2/0
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab34759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/1 - 1/20.

ターゲット情報

  • 関連性
    The members of the Hantavirus genus of the family Bunyaviridae are spherical, enveloped viruses containing tripartite negative-sense RNA as their genome. The three genomic RNA segments, designated L, M, and S, encode an RNA-dependent RNA polymerase, envelope glycoproteins (G1 and G2), and nucleocapsid (N) protein, respectively. Hantavirus infections can cause two serious and often fatal human diseases, hemorrhagic fever with renal syndrome and hantaviral pulmonary syndrome, characterized by lung damage and cardiac dysfunction. Humans are infected with hantaviruses from rodent reservoirs that are persistently infected without signs of disease.

参考文献

This product has been referenced in:
  • Perelygina L  et al. Persistent infection of human fetal endothelial cells with rubella virus. PLoS One 8:e73014 (2013). WB ; Human . Read more (PubMed: 23940821) »
  • Schlegel M  et al. Novel serological tools for detection of Thottapalayam virus, a Soricomorpha-borne hantavirus. Arch Virol 157:2179-87 (2012). Read more (PubMed: 22828778) »

See all 4 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab34759.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録