製品の概要

  • 製品名Anti-HAND1 antibody
    HAND1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HAND1
  • アプリケーション適用あり: WBmore details
  • 種交差性

    交差が予測される動物種: Mouse, Human
  • 免疫原

    3 synthetic peptides (Human) conjugated to KLH

  • ポジティブ・コントロール
    • Induced culture of E.coli. Heart tissue.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 24 kDa.

ターゲット情報

  • 機能Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box).
  • 組織特異性Heart.
  • 配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 翻訳後修飾Phosphorylation by PLK4 disrupts the interaction with MDFIC and leads to tranlocation into the nucleoplasm, allowing dimerization and transcription factor activity.
  • 細胞内局在Nucleus > nucleoplasm. Nucleus > nucleolus. Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • autonomic nervous system and neural crest derivatives-expressed protein 1 antibody
    • Basic helix loop helix transcription factor HAND1 antibody
    • bHLHa27 antibody
    • Class A basic helix-loop-helix protein 27 antibody
    • eHAND antibody
    • Extraembryonic tissues antibody
    • Extraembryonic tissues heart autonomic nervous system and neural crest derivatives expressed protein 1 antibody
    • HAND 1 antibody
    • HAND1 antibody
    • HAND1_HUMAN antibody
    • Heart and neural crest derivatives expressed 1 antibody
    • Heart and neural crest derivatives expressed protein 1 antibody
    • heart antibody
    • Heart- and neural crest derivatives-expressed protein 1 antibody
    • Hxt antibody
    • Thing 1 antibody
    • Thing1 antibody
    • Thing1 antibody
    see all

Anti-HAND1 antibody 画像

  • All lanes : Anti-HAND1 antibody (ab86009) at 1/1000 dilution

    Lane 1 : Uninduced culture
    Lane 2 : Induced culture of E.coli

    Secondary
    anti-Rabbit IgG HRP at 1/1000 dilution

    Predicted band size : 24 kDa

Anti-HAND1 antibody (ab86009) 使用論文

ab86009 has not yet been referenced specifically in any publications.

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