Haloperidol, D2 antagonist (ab120080)
Key features and details
- D2 antagonist
- CAS Number: 52-86-8
- Soluble in DMSO to 25 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Haloperidol, D2 antagonist -
製品の詳細
D2 antagonist -
生理活性の詳細
Dopamine antagonist with selectivity for D2-like receptors (Ki values are 1.2 (D2), 7 (D3), 2.3 (D4), 80 (D1) and 100 nM (D5)). Also NMDA antagonist.
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CAS 番号
52-86-8 -
構造式
製品の特性
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体系名
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one -
分子量
375.87 -
分子式
C21H23ClFNO2 -
PubChem 登録番号
3559 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 25 mM and in ethanol to 5 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Fc1ccc(cc1)C(=O)CCCN2CCC(O)(CC2)c3ccc(Cl)cc3 -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120080 は 1 報の論文で使用されています。
- Romanò N et al. Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. J Neurosci 33:4424-33 (2013). PubMed: 23467359