Anti-H5 (H5N1) 抗体 [8D2] (ab82455)

製品の概要

  • 製品名Anti-H5 (H5N1) antibody [8D2]
  • 製品の詳細
    Mouse monoclonal [8D2] to H5 (H5N1)
  • 特異性This antibody has been tested on the following strains: A/Chicken/Indonesia/Wates/1/2005 Neg A/Chicken/Indonesia/Wates/130/2005 Neg A/Duck/Vietnam/942B/2004 Pos A/Quail/Vietnam/826/2004 Pos A/Myanmar/1/2006 Neg A/Myanmar/4/2006 Neg A/Vietnam/1194/2004 Pos A/Vietnam/1203/2004 Pos A/Vietnam/1204/2004 Pos A/HK/213/03 Pos A/HK/156/97 Pos A/New Caledonia/20/99 (H1) Neg A/Wyoming/03/2003 (H3) Neg A/HK/1037/99 (H9) Neg Some of the results are based on information from customers and we have not tested them ourselves. The antibody has also been tested with recombinant hemagglutinins H1-H4 and H6-H15 and results were negative.
  • アプリケーション適用あり: ELISA, Dot blot, Inhibition Assaymore details
  • 種交差性
    Reacts with Influenza A H5 (H5N1)
  • 免疫原

    Purified avian Influenza Virus H5N1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名8D2
  • ミエローマSp2/0
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab82455 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
Dot blot Use at an assay dependent dilution.
Inhibition Assay Use at an assay dependent dilution.

ターゲット情報

  • 関連性Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability. H5 stands for the fifth of several known types of the viral protein hemagglutinin. This protein binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. It plays a major role in the determination of host range restriction and virulence and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
  • 細胞内局在Virion membrane
  • 別名
    • H5N1 haemagglutinin 5 antibody
    • H5N1 hemagglutinin 5 antibody
    • Haemagglutinin antibody
    • Hemagglutinin 5 antibody
    • Hemagglutinin antibody
    • Influenza a antibody
    • Influenza virus haemagglutinin 5 antibody
    • Influenza virus hemagglutinin antibody
    see all

Anti-H5 (H5N1) antibody [8D2] (ab82455) 使用論文

ab82455 has not yet been referenced specifically in any publications.

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Thank you for contacting us and your interest in our products.

I have the following answers to your questions:

Q1. Is ab82455 http://www.abcam.com/H5-H5N1-antibody-8D2-ab82455.htmlhttp://www.abcam.com/H5-H5N1-antibody-8D2-ab82455.html...

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Thank you for contacting us.

Q1. Is ab82455 Anti-H5 (H5N1) antibody [8D2] specific bind to ab123220 (Influenza A, Avian, Vietnam 1203/04, H5N1, Hemagglutinin protein)?

Answer: Yes, the antibody will recognize this protein, ab12322...

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Thank you for your enquiry.

I have contacted the originators of these antibodies, who have kindly provided the following testing results from various Influenza A virus strains with these antibodies:

ab59166 Influenza A Virus Hemag...

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Thank you for your inquiry. This antibody will recognize the native and recombinant H5, but we have not tested it on denatured samples. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice...

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Thank you for your inquiry. The immunogen has been received from our academic collaborator and unfortunately due to the confidentiality agreement I am not able to release the strain information. However, it is analog to A/chick/Scotland/72. I ho...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"