Anti-H2A.Z (acetyl K3 + K8 + K10 + K14) 抗体 (ab43983)

製品の概要

  • 製品名Anti-H2A.Z (acetyl K3 + K8 + K10 + K14) antibody
    H2A.Z 一次抗体 製品一覧
  • 製品の詳細
    Sheep polyclonal to H2A.Z (acetyl K3 + K8 + K10 + K14)
  • 特異性ab43983 was raised against an acetylated N-terminal H2A.Z peptide at residues K3, K8, K10 and K14. However, it is currently unclear if the antibody recognises all of these modifications or indeed unmodified H2A.Z. Customer feedback on this matter is appreciated.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Saccharomyces cerevisiae
    非交差種: Chicken, Cow
  • 免疫原

    Synthetic peptide corresponding to Saccharomyces cerevisiae H2A.Z aa 1-18 (N terminal) (acetyl K3 + K8 + K10 + K14).
    Sequence:

    SGK(Ac)AHGGK(Ac)GK(Ac)SGAK(Ac)DSGS-C


    Database link: P0C0S5

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab43983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa).

ターゲット情報

  • 機能Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
  • 配列類似性Belongs to the histone H2A family.
  • 翻訳後修飾Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression.
    Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis.
    Not phosphorylated.
  • 細胞内局在Nucleus. Chromosome.
  • Information by UniProt
  • 別名
    • H2A/z antibody
    • H2afz antibody
    • H2AZ antibody
    • H2AZ_HUMAN antibody
    • Histone H2A.Z antibody
    see all

Anti-H2A.Z (acetyl K3 + K8 + K10 + K14) antibody 画像

  • Anti-H2A.Z (acetyl K3 + K8 + K10 + K14) antibody (ab43983) at 2 µg/ml + S. cerevisiae lysate at 2 µg/ml

    Predicted band size : 14 kDa

Anti-H2A.Z (acetyl K3 + K8 + K10 + K14) antibody (ab43983) 使用論文

ab43983 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us and for your interest in our products.

Unfortunately we have yet to receieve the Abreview concerning ChIP for ab43983. All tested applications are specified on our datasheets, and these are updated as soon as any n...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"