Anti-H1N1 Influenza A virus Nucleocapsid protein 抗体 (ab104870)

製品の概要

  • 製品名Anti-H1N1 Influenza A virus Nucleocapsid protein antibody
    H1N1 Influenza A virus Nucleocapsid protein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to H1N1 Influenza A virus Nucleocapsid protein
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Influenza A
  • 免疫原

    Synthetic peptide derived from internal part of H1N1 Influenza A virus Nucleocapsid protein.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab104870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.

Dilute 1:200 - 1:2000

ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 関連性Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
  • 細胞内局在Virion. Host nucleus
  • 参照データベース
    • 別名
      • NP antibody
      • Nucleocapsid protein antibody
      • Nucleoprotein antibody
      • Protein N antibody

    Anti-H1N1 Influenza A virus Nucleocapsid protein antibody (ab104870) 使用論文

    ab104870 has not yet been referenced specifically in any publications.

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