製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GTSE1
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 691-720 of Human GTSE1.

  • ポジティブ・コントロール
    • Hela cell lysate; Human brain tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 関連性
    GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it co-localizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. Overexpression of GTSE1 delays G2/M phase progression.
  • 細胞内局在
    Cytoplasm. Note: Associated with microtubules
  • 参照データベース
  • 別名
    • B99 antibody
    • B99 homolog antibody
    • G 2 and S phase expressed 1 antibody
    • G two S phase expressed protein 1 antibody
    • GTSE 1 antibody
    see all

画像

  • Anti-GTSE1 antibody (ab103232) at 1/100 dilution + Hela cell lysate at 35 µg

    Predicted band size : 77 kDa
  • ab103232, at 1/50 dilution, staining GTSE1 in formalin fixed, paraffin embedded Human brain tissue by Immunohistochemistry, using a peroxidase conjugated secondary antibody and DAB staining.

参考文献

This product has been referenced in:
  • Penna I  et al. The inhibition of 45A ncRNA expression reduces tumor formation, affecting tumor nodules compactness and metastatic potential in neuroblastoma cells. Oncotarget 8:8189-8205 (2017). WB, IHC . Read more (PubMed: 28029658) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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