製品の概要

  • 製品名
    GTP (Guanosine-5'-triphosphate)
  • 製品の詳細
    Purine nucleoside. Essential in many physiological functions.
  • 別名
    • Guanosine-5'-triphosphate
  • 生理活性の詳細
    Purine nucleoside. Essential in many physiological functions including RNA synthesis and cell signaling. Also acts as a metabolic energy source and induces apoptosis.

製品の特性

  • 体系名
    Guanosine 5'-triphosphate ammonium salt
  • 分子量
    523.18
  • 構造式
    Chemical Structure
  • 分子式
    C10H16N5O14P3.xNH3
  • CAS 番号
    86-01-1
  • PubChem 登録番号
    6830
  • 保存方法
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性
    Soluble in water to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    N.N.N.O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n2cnc1c2N=C(N)NC1=O)C(O)[C@H]3O
  • 由来

    Synthetic

  • 研究分野

参考文献

ab120628 has not yet been referenced specifically in any publications.

レビューと Q&A

Microtubules (MT) were isolated from SH-SY5y cells using 0.1mM GTP and Paclitaxel (ab120143) as per the protocol outlined in: Sloboda RD. 2014b. Isolation of microtubules and microtubule-associated proteins using paclitaxel. Cold Spring Harb Protoc doi: 10.1101/pdb .prot081190.
Following isolation, 20 μg of protein from the MT extract was immunoblotted for detecting B-3-Tubulin (Primary antibody - 1:500 dilution overnight, Secondary antibody (ab6728) - 1: 2000 dilution for 1h).
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投稿 Feb 28 2018

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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