製品の概要

  • 製品名
    Anti-GTF2IRD2 antibody
  • 製品の詳細
    Rabbit polyclonal to GTF2IRD2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 820-850 of Human GTF2IRD2

  • ポジティブ・コントロール
    • K562 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab103946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 107 kDa.

ターゲット情報

  • 関連性
    GTF2IRD2 N-terminal half contains a leucine zipper motif, followed by 2 helix-loop-helix motifs (I repeats) that share homology with the TFII-I family of transcription factors. The C-terminal half of GTF2IRD2A contains a CHARLIE8 transposable element-like sequence, including 3 transposase-related domains that may be functional, and a BED zinc finger DNA-binding motif. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. There are six different isoforms, generated by alternative splicing.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • FLJ21423 antibody
    • FLJ37938 antibody
    • FP630 antibody
    • general transcription factor II i repeat domain 2 alpha antibody
    • general transcription factor II I repeat domain-containing protein 2A antibody
    • GTF2I repeat domain containing 2 antibody
    • GTF2I repeat domain containing protein 2A antibody
    • GTF2IRD2 alpha antibody
    • GTF2IRD2A antibody
    • MGC75203 antibody
    • Transcription factor GTF2IRD2 alpha antibody
    • transcription factor GTF2IRD2 antibody
    see all

画像

  • Anti-GTF2IRD2 antibody (ab103946) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 107 kDa

プロトコール

参考文献

ab103946 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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