製品の概要

  • 製品名Anti-GSTM1 + GSTM2 antibody
  • 製品の詳細
    Goat polyclonal to GSTM1 + GSTM2
  • 特異性This antibody is expected to recognise both reported variants of human GSTM1 protein (NP_000552; NP_666533) and GSTM2 protein (NP_000848).
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide:

    CVFSKMAVWGNK

    from the C Terminus of the protein (Human).

  • ポジティブ・コントロール
    • Human liver and lung lysates for Western blot.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab27489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 26 kDa).

ターゲット情報

  • 関連性Glutathione S transferases are encoded by two distinct supergene families and a total of eight distinct classes of the soluble cytoplasmic mammalian glutathione S transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of these enzymes, to which GSTM1 and 2 belong, functions in the detoxification of electrophilic compounds by conjugation with glutathione. The genes encoding the mu class of enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs and null mutations of this gene have been linked with an increase in a number of cancers.
  • 細胞内局在Cytoplasmic
  • 参照データベース
  • 別名
    • Glutathione S alkyltransferase M1 antibody
    • Glutathione S alkyltransferase M2 antibody
    • Glutathione S transferase M1 antibody
    • Glutathione S transferase Mu 1 antibody
    • Glutathione S transferase Mu 2 antibody
    • GST class mu 1 antibody
    • GSTM antibody
    • GTH4 antibody
    • GTM1 antibody
    • S(hydroxyalkyl) glutathione lyase antibody
    see all

Anti-GSTM1 + GSTM2 antibody 画像

  • Anti-GSTM1 + GSTM2 antibody (ab27489) at 0.3 µg/ml + human lung lysate (35µg protein in RIPA buffer).

    Predicted band size : 26 kDa
    Observed band size : 26 kDa

Anti-GSTM1 + GSTM2 antibody (ab27489) 使用論文

This product has been referenced in:
  • Shan Y  et al. Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model. Antioxid Redox Signal 19:1481-93 (2013). Read more (PubMed: 23350650) »
  • Yang Y  et al. Glutathione S-Transferase-{mu}1 Regulates Vascular Smooth Muscle Cell Proliferation, Migration, and Oxidative Stress. Hypertension : (2009). Read more (PubMed: 19822795) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"