Anti-Growth Hormone 抗体 [KT34] (HRP) (ab106749)

製品の概要

  • 製品名Anti-Growth Hormone antibody [KT34] (HRP)
    Growth Hormone 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [KT34] to Growth Hormone (HRP)
  • 標識HRP
  • アプリケーション適用あり: WB, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Human Growth Hormone

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 25 kDa.
Sandwich ELISA 1/1000. Can be paired for Sandwich ELISA with Rat monoclonal [KT19] to Growth Hormone (ab106720). Can be used as detection antibody when paired with ab106720.

ターゲット情報

  • 機能Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
  • 関連疾患Defects in GH1 are a cause of growth hormone deficiency isolated type 1A (IGHD1A) [MIM:262400]; also known as pituitary dwarfism I. IGHD1A is an autosomal recessive deficiency of GH which causes short stature. IGHD1A patients have an absence of GH with severe dwarfism and often develop anti-GH antibodies when given exogenous GH.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH. Dwarfism is less severe than in IGHD1A and patients usually respond well to exogenous GH.
    Defects in GH1 are the cause of Kowarski syndrome (KWKS) [MIM:262650]; also known as pituitary dwarfism VI.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 2 (IGHD2) [MIM:173100]. IGHD2 is an autosomal dominant deficiency of GH which causes short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
  • 配列類似性Belongs to the somatotropin/prolactin family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • gH antibody
    • GH-N antibody
    • GH1 antibody
    • GHN antibody
    • Growth hormone 1 antibody
    • Growth hormone antibody
    • Growth hormone, normal antibody
    • Growth hormone, pituitary antibody
    • HG1 antibody
    • hGH-N antibody
    • IGHD1B antibody
    • Pituitary growth hormone antibody
    • RNGHGP antibody
    • SOMA_HUMAN antibody
    • Somatotropin antibody
    see all

Anti-Growth Hormone antibody [KT34] (HRP) 画像

  • Sandwich ELISA using a plate coated with a Rat IgG1 monoclonal and HRP conjugated ab106749 at 1/1000 dilution.

Anti-Growth Hormone antibody [KT34] (HRP) (ab106749) 使用論文

ab106749 has not yet been referenced specifically in any publications.

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