製品の概要

  • 製品名
    Anti-GRLF1 antibody [2389D3a]
    GRLF1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2389D3a] to GRLF1
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment of Human GRLF1

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate), pH 7.4
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    ab58674 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • ポリ/モノ
    モノクローナル
  • クローン名
    2389D3a
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab58674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
Dot blot
  • 追加情報
    Dot: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects a band of approximately 35 kDa for the recombinant fragment (predicted molecular weight for the full length protein: 172 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.
    • 配列類似性
      Contains 4 FF domains.
      Contains 1 Rho-GAP domain.
    • 翻訳後修飾
      Tyrosine phosphorylated.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在
      Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ARHGAP35 antibody
      • GAP associated protein p190 antibody
      • Glucocorticoid receptor DNA binding factor 1 antibody
      • Glucocorticoid receptor DNA-binding factor 1 antibody
      • Glucocorticoid receptor repression factor 1 antibody
      • GRF 1 antibody
      • GRF-1 antibody
      • GRF1 antibody
      • GRLF 1 antibody
      • GRLF1 antibody
      • GRLF1_HUMAN antibody
      • KIAA1722 antibody
      • MGC10745 antibody
      • p190 A antibody
      • p190-A antibody
      • P190A antibody
      • P190A, rat, homolog of antibody
      • p190ARhoGAP antibody
      • p190RhoGAP antibody
      • Rho GAP p190A antibody
      • Rho GTPase-activating protein 35 antibody
      see all

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    プロトコール

    参考文献

    ab58674 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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