製品の概要

  • 製品名Anti-GRK6 antibody [EPR2046(2)]
    GRK6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2046(2)] to GRK6
  • アプリケーション適用あり: WB, ICC/IFmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A synthetic peptide corresponding to residues in human GRK6.

  • ポジティブ・コントロール
    • U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
ICC/IF 1/250 - 1/500.
  • 追加情報Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 機能Specifically phosphorylates the activated forms of G protein-coupled receptors.
    • 組織特異性Widely expressed.
    • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
      Contains 1 RGS domain.
    • 翻訳後修飾It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 製品の状態There are 2 isoforms produced by alternative splicing.
    • 別名
      • FLJ32135 antibody
      • G protein coupled receptor kinase 6 antibody
      • G protein coupled receptor kinase GRK6 antibody
      • G protein-coupled receptor kinase 6 antibody
      • G protein-coupled receptor kinase GRK6 antibody
      • Gprk6 antibody
      • Grk6 antibody
      • GRK6_HUMAN antibody
      see all

    Anti-GRK6 antibody [EPR2046(2)] 画像

    • All lanes : Anti-GRK6 antibody [EPR2046(2)] (ab109302) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 66 kDa

    Anti-GRK6 antibody [EPR2046(2)] (ab109302) 使用論文

    This product has been referenced in:
    • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . Read more (PubMed: 23576548) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109302.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"