Rabbit monoclonal [EPR2046(2)] to GRK6
Synthetic peptide within Human GRK6 aa 50-150. The exact sequence is proprietary.
U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
1/250 - 1/500.
Is unsuitable for Flow Cyt,IHC-P or IP.
Specifically phosphorylates the activated forms of G protein-coupled receptors.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. Contains 1 RGS domain.
It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
Information by UniProt
There are 2 isoforms produced by alternative splicing.
G protein coupled receptor kinase 6 antibody
G protein coupled receptor kinase GRK6 antibody
This product has been referenced in:
et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013).
Read more (PubMed: 23576548) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"