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RabMAb

Anti-GRK6 抗体 [EPR2046(2)] (ab109302)

製品の概要

  • 製品名
    Anti-GRK6 antibody [EPR2046(2)]
    GRK6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR2046(2)] to GRK6
  • アプリケーション
    適用あり: WB, ICC/IFmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A synthetic peptide corresponding to residues in human GRK6.

  • ポジティブ・コントロール
    • U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
ICC/IF 1/250 - 1/500.
  • 追加情報
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 機能
      Specifically phosphorylates the activated forms of G protein-coupled receptors.
    • 組織特異性
      Widely expressed.
    • 配列類似性
      Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
      Contains 1 RGS domain.
    • 翻訳後修飾
      It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 製品の状態
      There are 2 isoforms produced by alternative splicing.
    • 別名
      • FLJ32135 antibody
      • G protein coupled receptor kinase 6 antibody
      • G protein coupled receptor kinase GRK6 antibody
      • G protein-coupled receptor kinase 6 antibody
      • G protein-coupled receptor kinase GRK6 antibody
      • Gprk6 antibody
      • Grk6 antibody
      • GRK6_HUMAN antibody
      see all

    画像

    • All lanes : Anti-GRK6 antibody [EPR2046(2)] (ab109302) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 66 kDa

    参考文献

    This product has been referenced in:
    • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . Read more (PubMed: 23576548) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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