Anti-GRK6 抗体 - Carboxyterminal end (ab38291)
製品の概要
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製品名Anti-GRK6 antibody - Carboxyterminal end
GRK6 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to GRK6 - Carboxyterminal end
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アプリケーション適用あり: ELISA, WB, IHC-Pmore details
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種交差性交差種: Mouse, Human
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免疫原
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected within aa 500~600 of human GRK6.
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ポジティブ･コントロール
- HeLa cell lysate, Mouse heart tissue lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... -
精製度Protein G purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab38291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA | 1/1000. | |
| WB | 1/100 - 1/500. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa). | |
| IHC-P | 1/50 - 1/100. |
ターゲット情報
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機能Specifically phosphorylates the activated forms of G protein-coupled receptors.
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組織特異性Widely expressed.
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配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.
Contains 1 RGS domain. -
翻訳後修飾It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
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細胞内局在Membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 2870 Human
- Entrez Gene: 26385 Mouse
- Omim: 600869 Human
- SwissProt: P43250 Human
- SwissProt: O70293 Mouse
- Unigene: 235116 Human
- Unigene: 10193 Mouse
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製品の状態There are 2 isoforms produced by alternative splicing.
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別名
- FLJ32135 antibody
- G protein coupled receptor kinase 6 antibody
- G protein coupled receptor kinase GRK6 antibody
see all
Anti-GRK6 antibody - Carboxyterminal end 画像
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Western blot - GRK6 antibody (ab38291)All lanes : Anti-GRK6 antibody - Carboxyterminal end (ab38291) at 1/100 dilution
Lane 1 : HeLa cell lysate.
Lane 2 : Mouse heart tissue lysate.
Secondary
HRP-anti-rabbit.
Developed using the ECL technique
Predicted band size : 66 kDa
Observed band size : 66 kDa -
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRK6 antibody (ab38291)ab38291 (1/50) staining human cancer tissue by immunohistochemistry, formalin-fixed, paraffin-embedded tissue. The breast carcinoma tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
Anti-GRK6 antibody - Carboxyterminal end (ab38291) 使用論文
This product has been referenced in:
- Tiedemann RE et al. Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6. Blood 115:1594-604 (2010). WB ; Human . Read more (PubMed: 19996089) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"