製品の概要

  • 製品名Anti-GRK2 antibody
    GRK2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to GRK2
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Hamster, Cow, Dog, Chimpanzee, Macaque Monkey
  • 免疫原

    Synthetic peptide:

    C-RDAYREAQQLVQR

    , corresponding to internal sequence amino acids 648-660 of Human GRK2.

  • ポジティブ・コントロール
    • Human lysates of Burkitt's lymphoma cell line Daudi

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: detection limit dilution 1/16000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 80 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
    • 組織特異性Expressed in peripheral blood leukocytes.
    • 配列類似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 PH domain.
      Contains 1 protein kinase domain.
      Contains 1 RGS domain.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ADRBK1 antibody
      • Adrenergic beta receptor kinase 1 antibody
      • ARBK1_HUMAN antibody
      • BARK antibody
      • BARK1 antibody
      • Beta adrenergic receptor kinase 1 antibody
      • Beta ARK 1 antibody
      • Beta ARK1 antibody
      • Beta-adrenergic receptor kinase 1 antibody
      • Beta-ARK-1 antibody
      • FLJ16718 antibody
      • G protein coupled receptor kinase 2 antibody
      • G-protein coupled receptor kinase 2 antibody
      • GRK2 antibody
      see all

    Anti-GRK2 antibody 画像

    Anti-GRK2 antibody (ab47999) 使用論文

    ab47999 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab47999.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"