製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to GRIK3
  • 由来種
    Goat
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human, Cynomolgus monkey
  • 免疫原

    Synthetic peptide: C-

    KIRQLPIDSDDSRP

    , corresponding to internal sequence amino acids 203-216 of human GRIK3 (NP_000822.2).

  • ポジティブ・コントロール
    • Rat brain and mouse brain lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1:64,000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 104 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
    • 配列類似性
      Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK3 subfamily.
    • 細胞内局在
      Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • EAA5 antibody
      • Excitatory amino acid receptor 5 antibody
      • GLR 7 antibody
      • GLR7 antibody
      • GLU R7 antibody
      • GLUR 7 antibody
      • GluR 7a antibody
      • GluR-7 antibody
      • GluR7 antibody
      • GluR7a antibody
      • Glutamate receptor 7 antibody
      • Glutamate receptor antibody
      • Glutamate receptor ionotropic kainate 3 antibody
      • GRIK 3 antibody
      • GRIK3 antibody
      • GRIK3_HUMAN antibody
      • ionotropic kainate 3 antibody
      see all

    画像

    • Anti-GRIK3 antibody (ab82148) at 0.3 µg/ml + Rat brain lysate in RIPA buffer at 35 µg

      Developed using the ECL technique.

      Predicted band size: 104 kDa
      Observed band size: 110 kDa (why is the actual band size different from the predicted?)



      An additional band of unknown identity was also consistently observed at 39 kDa. This band was successfully blocked by incubation with the immunizing peptide.

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    参考文献

    This product has been referenced in:

    See 1 Publication for this product

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