製品の概要

  • 製品名Anti-GRHPR antibody [9G2]
    GRHPR 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [9G2] to GRHPR
  • アプリケーション適用あり: WB, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein of Human GRHPR produced in HEK293T cells (NP_036335).

  • ポジティブ・コントロール
    • HEK293T cells transfected with GRHPR
  • 特記事項Concentration: 0.5~1.0 mg/ml (Lot Dependent)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119081 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Predicted molecular weight: 36 kDa.
Flow Cyt 1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
  • 組織特異性Ubiquitous. Most abundantly expressed in the liver.
  • 関連疾患Defects in GRHPR are the cause of hyperoxaluria primary type 2 (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L-glycerate.
  • 配列類似性Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • GLXR antibody
    • glycerate 2 dehydrogenase antibody
    • GLYD antibody
    • Glyoxylate reductase/hydroxypyruvate reductase antibody
    • Grhpr antibody
    • GRHPR_HUMAN antibody
    • OTTHUMP00000021379 antibody
    • OTTHUMP00000021380 antibody
    • OTTHUMP00000046131 antibody
    • PH 2 antibody
    • PH2 antibody
    • Primary hyperoxaluria type 2 antibody
    see all

Anti-GRHPR antibody [9G2] 画像

  • All lanes : Anti-GRHPR antibody [9G2] (ab119081) at 1/2000 dilution

    Lane 1 : HEK293T cells transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cells transfected with pCMV6-ENTRY GRHPR

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 36 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC200963)
  • HEK293T cells transfected with either RC200963 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by ab119081 at a dilution of 1/100, and then analyzed by flow cytometry.

Anti-GRHPR antibody [9G2] (ab119081) 使用論文

ab119081 has not yet been referenced specifically in any publications.

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