The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
機能Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
組織特異性Constituvely expressed in NK cells.
配列類似性Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain.
細胞内局在Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes.