製品の概要

  • 製品名Anti-GRAF antibody
    GRAF 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to GRAF
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human GRAF (AAH68555.1, amino acids 1-759)

  • ポジティブ・コントロール
    • GRAF transfected 293T cell lysate, HepG2 cell lysate and Human placenta tissue lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89783 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: Isoform 2, 86 kDa; Isoform 1, 94 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能GTPase-activating protein for RHOA and CDC42.
    • 関連疾患Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
    • 配列類似性Contains 1 PH domain.
      Contains 1 Rho-GAP domain.
      Contains 1 SH3 domain.
    • 細胞内局在Cell junction > focal adhesion. Cytoplasm > cytoskeleton. Colocalizes with actin stress fibers and cortical actin structures.
    • Information by UniProt
    • 参照データベース
    • 別名
      • arhgap26 antibody
      • FLJ42530 antibody
      • GRAF antibody
      • GRAF1 antibody
      • GTPase regulator associated with focal adhesion kinase antibody
      • GTPase regulator associated with focal adhesion kinase pp125(FAK) antibody
      • KIAA0621 antibody
      • oligophrenin 1 like protein antibody
      • Oligophrenin-1-like protein antibody
      • oligophrenin1like protein antibody
      • OPHN1L antibody
      • OPHN1L1 antibody
      • RHG26_HUMAN antibody
      • Rho GTPase activating protein 26 antibody
      • Rho GTPase activating protein26 antibody
      • Rho GTPase-activating protein 26 antibody
      • Rho-type GTPase-activating protein 26 antibody
      see all

    Anti-GRAF antibody 画像

    • Anti-GRAF antibody (ab89783) at 1 µg/ml + human placenta tissue lysate at 50 µg

      Predicted band size : 86 kDa
      Observed band size : 76 kDa (why is the actual band size different from the predicted?)
    • Anti-GRAF antibody (ab89783) at 1 µg/ml + HepG2 cell lysate at 50 µg

      Predicted band size : 86 kDa
      Observed band size : 86 kDa
    • All lanes : Anti-GRAF antibody (ab89783) at 1 µg/ml

      Lane 1 : GRAF transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 86 kDa
      Observed band size : 86 kDa

    Anti-GRAF antibody (ab89783) 使用論文

    This product has been referenced in:
    • Cai B  et al. GRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation. Front Cell Dev Biol 2:22 (2014). Read more (PubMed: 25364729) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab89783.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"