製品の概要

  • 製品名Anti-GRAF antibody
    GRAF 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to GRAF
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    KTGLIPENYVEFL

    , corresponding to C terminal amino acids 802-814 of Human GRAF.

  • ポジティブ・コントロール
    • Heart lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 94 kDa).

ターゲット情報

  • 機能GTPase-activating protein for RHOA and CDC42.
  • 関連疾患Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
  • 配列類似性Contains 1 PH domain.
    Contains 1 Rho-GAP domain.
    Contains 1 SH3 domain.
  • 細胞内局在Cell junction > focal adhesion. Cytoplasm > cytoskeleton. Colocalizes with actin stress fibers and cortical actin structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • arhgap26 antibody
    • FLJ42530 antibody
    • GRAF antibody
    • GRAF1 antibody
    • GTPase regulator associated with focal adhesion kinase antibody
    • GTPase regulator associated with focal adhesion kinase pp125(FAK) antibody
    • KIAA0621 antibody
    • oligophrenin 1 like protein antibody
    • Oligophrenin-1-like protein antibody
    • oligophrenin1like protein antibody
    • OPHN1L antibody
    • OPHN1L1 antibody
    • RHG26_HUMAN antibody
    • Rho GTPase activating protein 26 antibody
    • Rho GTPase activating protein26 antibody
    • Rho GTPase-activating protein 26 antibody
    • Rho-type GTPase-activating protein 26 antibody
    see all

Anti-GRAF antibody 画像

  • All lanes : Anti-GRAF antibody (ab15916) at 0.3 µg/ml

    Lane 1 : (A) Human Heart lysate
    Lane 2 : (B) Human Heart lysate with immunizing peptide

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 94 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 16 kDa. We are unsure as to the identity of these extra bands.

Anti-GRAF antibody (ab15916) 使用論文

ab15916 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab15916.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"