Anti-GPSM1 抗体 (ab111022)

製品の概要

  • 製品名Anti-GPSM1 antibody
    GPSM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GPSM1
  • アプリケーション適用あり: IHC-Fr, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, a wide range of other species
  • 免疫原

    Synthetic peptide, derived from an internal region of Human GPSM1 (UniProt ID: Q86YR5).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.
WB 1/1000 - 1/5000. Predicted molecular weight: 75 kDa.
IHC-P 1/100 - 1/1000.

ターゲット情報

  • 機能Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
  • 組織特異性Expressed in intestinal cells.
  • 配列類似性Belongs to the GPSM family.
    Contains 4 GoLoco domains.
    Contains 9 TPR repeats.
  • ドメインThe GoLoco domains mediate interaction with G(i/o) alpha (By similarity). The GoLoco domains are essential for the GDI activity toward G(i/o) alpha.
  • 翻訳後修飾Phosphorylation regulates interaction with G(i/o) alpha.
  • 細胞内局在Cytoplasm > cytosol. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activator of G-protein signaling 3 antibody
    • AGS3 antibody
    • AGS3 homolog antibody
    • C10a antibody
    • G protein signaling modulator 1 (AGS3 like, C. elegans) antibody
    • G-protein-signaling modulator 1 antibody
    • GPSM1 antibody
    • GPSM1_HUMAN antibody
    see all

Anti-GPSM1 antibody (ab111022) 使用論文

ab111022 has not yet been referenced specifically in any publications.

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Mouse Embryo (day 8.5))
Specification Mouse Embryo (day 8.5)
Fixative Paraformaldehyde
Blocking step Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 37°C
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Derek Passer

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投稿 Oct 13 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"