製品の概要

  • 製品名
    Anti-GPS2 antibody [clone 1E2]
    GPS2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [clone 1E2] to GPS2
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 161-311 of Human GPS2

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB 1/500 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

ターゲット情報

  • 関連性
    GPS2(G-protein pathway suppressor 2), also called AMF1, is a human nuclear protein of 327 amino acids involved in G protein-mitogen-activated protein kinase(MAPK) signalling cascades. This protein is an integral subunit of the NCOR1-HDAC3(nuclear receptor corepressor 1-histone deacetylase 3) complex which inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1(activator protein 1) function.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • AMF 1 antibody
    • AMF1 antibody
    • G protein pathway suppressor 2 antibody
    • GPS 2 antibody

画像

  • Anti-GPS2 antibody [clone 1E2] (ab53406) at 1/500 dilution + HeLa cell lysates at 100 µg

    Secondary
    HRP-conjugated goat anti-mouse
    Developed using the ECL technique

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

プロトコール

参考文献

This product has been referenced in:
  • Rössger K  et al. A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice. Nat Commun 4:2825 (2013). WB ; Human . Read more (PubMed: 24281397) »

See 1 Publication for this product

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