製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GPNMB
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 143 - 192 of Human GPNMB (NP_001005340).

  • ポジティブ・コントロール
    • PANC1 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Could be a melanogenic enzyme.
  • 組織特異性
    Not restricted to the melanocytic lineage.
  • 配列類似性
    Belongs to the PMEL/NMB family.
    Contains 1 PKD domain.
  • 発生段階
    Expression in poorly metastatic melanoma cell lines; no expression in highly metastatic melanoma cell lines.
  • 細胞内局在
    Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Glycoprotein (transmembrane) nmb antibody
    • Glycoprotein nmb antibody
    • Glycoprotein nmb like protein antibody
    • Gpnmb antibody
    • GPNMB_HUMAN antibody
    • HGFIN antibody
    • NMB antibody
    • Osteoactivin antibody
    • Transmembrane glycoprotein antibody
    • Transmembrane glycoprotein HGFIN antibody
    • Transmembrane glycoprotein NMB antibody
    see all

画像

  • Anti-GPNMB antibody (ab98856) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 64 kDa

プロトコール

参考文献

This product has been referenced in:
  • Epple LM  et al. Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. PLoS One 7:e42064 (2012). WB . Read more (PubMed: 22848702) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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