製品の概要
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製品名Anti-GPNMB antibody
GPNMB 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to GPNMB
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cat, Dog, Pig
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免疫原
Synthetic peptide corresponding to a region within N terminal amino acids 143 - 192 of Human GPNMB (NP_001005340).
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ポジティブ･コントロール
- PANC1 cell lysate
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: None
Constituents: 2% Sucrose, PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab98856 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T. |
ターゲット情報
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機能Could be a melanogenic enzyme.
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組織特異性Not restricted to the melanocytic lineage.
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配列類似性Belongs to the PMEL/NMB family.
Contains 1 PKD domain. -
発生段階Expression in poorly metastatic melanoma cell lines; no expression in highly metastatic melanoma cell lines.
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細胞内局在Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- Information by UniProt
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参照データベース
- Entrez Gene: 10457 Human
- Entrez Gene: 93695 Mouse
- Entrez Gene: 113955 Rat
- Omim: 604368 Human
- SwissProt: Q14956 Human
- SwissProt: Q99P91 Mouse
- SwissProt: Q6P7C7 Rat
- Unigene: 190495 Human
see all -
別名
- Glycoprotein (transmembrane) nmb antibody
- Glycoprotein nmb antibody
- Glycoprotein nmb like protein antibody
see all
Anti-GPNMB antibody 画像
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Western blot - GPNMB antibody (ab98856)Anti-GPNMB antibody (ab98856) at 1 µg/ml + PANC1 cell lysate at 10 µg
Predicted band size : 64 kDa
プロトコール
Anti-GPNMB antibody (ab98856) 使用論文
This product has been referenced in:
- Epple LM et al. Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. PLoS One 7:e42064 (2012). WB . Read more (PubMed: 22848702) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"