製品の概要

  • 製品名Anti-GPNMB antibody
    GPNMB 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to GPNMB
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human, Recombinant Fragment
  • 免疫原

    Recombinant fragment: RCQKEDANGN IVYEKNCRNE AGLSADPYVY NWTAWSEDSD GENGTGQSHH NVFPDGKPFP HHPGWRRWNF IYVFHTLGQY FQKLGRCSVR VSVNTANVTL , corresponding to amino acids 104-204 of Human GPNMB

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
WB
  • 追加情報IHC-P: Use at an assay dependent dilution (PMID 20133820).
    WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Could be a melanogenic enzyme.
    • 組織特異性Not restricted to the melanocytic lineage.
    • 配列類似性Belongs to the PMEL/NMB family.
      Contains 1 PKD domain.
    • 発生段階Expression in poorly metastatic melanoma cell lines; no expression in highly metastatic melanoma cell lines.
    • 細胞内局在Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Glycoprotein (transmembrane) nmb antibody
      • Glycoprotein nmb antibody
      • Glycoprotein nmb like protein antibody
      • Gpnmb antibody
      • GPNMB_HUMAN antibody
      • HGFIN antibody
      • NMB antibody
      • Osteoactivin antibody
      • Transmembrane glycoprotein antibody
      • Transmembrane glycoprotein HGFIN antibody
      • Transmembrane glycoprotein NMB antibody
      see all

    Anti-GPNMB antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56584 GPNMB antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-GPNMB antibody (ab56584) 使用論文

    This product has been referenced in:
    • Tyburczy ME  et al. Novel Proteins Regulated by mTOR in Subependymal Giant Cell Astrocytomas of Patients with Tuberous Sclerosis Complex and New Therapeutic Implications. Am J Pathol 176:1878-90 (2010). IHC-P ; Human . Read more (PubMed: 20133820) »

    See 1 Publication for this product

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