製品の概要

  • 製品名Anti-GPCR MRGX2 antibody
    GPCR MRGX2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GPCR MRGX2
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to a region from the C terminal cytoplasmic domain of Human GPCR MRGX2, conjugated to KLH.

  • ポジティブ・コントロール
    • Human spinal Cord, DRG tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab116712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
  • 組織特異性Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • G protein coupled receptor MRGX 2 antibody
    • G protein coupled receptor MRGX2 antibody
    • Mas related G protein coupled receptor member X2 antibody
    • Mas related gene MRGX 2 antibody
    • Mas related gene MRGX2 antibody
    • MAS related GPR member X2 antibody
    • Mas-related G-protein coupled receptor member X antibody
    • Mas-related G-protein coupled receptor member X2 antibody
    • MRGPRX 2 antibody
    • MRGPRX2 antibody
    • MRGX 2 antibody
    • MRGX2 antibody
    • MRGX2_HUMAN antibody
    see all

Anti-GPCR MRGX2 antibody 画像

  • Human spinal cord, DRG (formalin fixed, paraffin embedded tissue) stained with ab116712 at 20 µg/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GPCR MRGX2 antibody (ab116712) 使用論文

ab116712 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116712.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"