製品の概要

  • 製品名Anti-GPCR GPRC5B antibody
    GPCR GPRC5B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GPCR GPRC5B
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of human GPCR GPRC5B.

  • ポジティブ・コントロール
    • Extracts from HUVEC, 293 and Jurkat cells. MCF-7 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab75427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.

ターゲット情報

  • 機能Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 組織特異性Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.
  • 配列類似性Belongs to the G-protein coupled receptor 3 family.
  • 細胞内局在Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • 参照データベース
  • 別名
    • A 69G12.1 antibody
    • A-69G12.1 antibody
    • G protein coupled receptor family C group 1 member B antibody
    • G protein coupled receptor family C group 5 member B antibody
    • G-protein coupled receptor family C group 5 member B antibody
    • GPC5B_HUMAN antibody
    • Gprc5b antibody
    • LOC51704 antibody
    • RAIG-2 antibody
    • RAIG2 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 2 protein antibody
    see all

Anti-GPCR GPRC5B antibody 画像

  • ab75427 staining MCF7 cells at 1/500 dilution, in the absence and presence of the immunising peptide
  • All lanes : Anti-GPCR GPRC5B antibody (ab75427) at 1/500 dilution

    Lane 1 : extracts from HUVEC cells
    Lane 2 : extracts from 293 cells
    Lane 3 : extracts from Jurkat cells
    Lane 4 : extracts from Jurkat cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 45 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.

Anti-GPCR GPRC5B antibody (ab75427) 使用論文

ab75427 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"