製品の概要

  • 製品名Anti-GPCR GPR37 antibody
    GPCR GPR37 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GPCR GPR37
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region from the N-terminal extracellular domain of Human GPCR GPR37.

  • ポジティブ・コントロール
    • Human brain cortex tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -80°C.
  • バッファーPreservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Orphan receptor. May have a unique functional role in the central nervous system.
  • 組織特異性Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.
  • 細胞内局在Cell membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EDNRBL antibody
    • Endothelin B receptor like protein 1 antibody
    • Endothelin B receptor-like protein 1 antibody
    • Endothelin receptor type B like antibody
    • ETBR LP 1 antibody
    • ETBR-LP-1 antibody
    • ETBRLP1 antibody
    • G protein coupled receptor 37 antibody
    • G protein coupled receptor 37 endothelin receptor type B like antibody
    • Gpr37 antibody
    • GPR37_HUMAN antibody
    • hET(B)R LP antibody
    • hET(B)RLP antibody
    • PAELR antibody
    • Parkin associated endothelin receptor like receptor antibody
    • Parkin-associated endothelin receptor-like receptor antibody
    • Probable G protein coupled receptor 37 antibody
    • Probable G-protein coupled receptor 37 antibody
    see all

Anti-GPCR GPR37 antibody 画像

  • ab115902, at 3 µg/ml, staining GPCR GPR37 in Formalin-fixed, Paraffin-embedded Human brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GPCR GPR37 antibody (ab115902) 使用論文

ab115902 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"