製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GPCR GPR124
  • アプリケーション
    適用あり: WB, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Synthetic peptide (Human) of 14 amino acids from the central region

  • ポジティブ・コントロール
    • Rat Kidney Tissue Lysate Human bladder tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab67280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 142 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
  • 組織特異性
    Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
  • 配列類似性
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • ドメイン
    Binds to DLG1 through its PDZ-binding motif.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp434C211 antibody
    • DKFZp434J0911 antibody
    • FLJ14390 antibody
    • G protein coupled receptor 124 antibody
    • G-protein coupled receptor 124 antibody
    • GP124_HUMAN antibody
    • GPR 124 antibody
    • Gpr124 antibody
    • KIAA1531 antibody
    • TEM 5 antibody
    • TEM5 antibody
    • Tumor endothelial marker 5 antibody
    • Tumor endothelial marker 5 precursor antibody
    see all

画像

  • Immunofluorescence of GPCR GPR124 in Human bladder tissue with ab67280 at 20 ug/mL.

  • Lane 1 : Anti-GPCR GPR124 antibody (ab67280) at 2 µg/ml
    Lane 2 : Anti-GPCR GPR124 antibody (ab67280) at 4 µg/ml

    Lane 1 : Rat kidney tissue lysate
    Lane 2 : Rat kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 142 kDa
    Observed band size : 176,180 kDa (why is the actual band size different from the predicted?)
  • ab67280 at 5µg/ml staining of  GPCR GPR124 in human bladder tissue using IHC-P.

参考文献

ab67280 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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