製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to GPCR GPR120
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 1 - 41 of Human GPCR GPR120 (NP_859529).

  • ポジティブ・コントロール
    • WB: HeLa cell lysate IHC-P: Human prostate adenocarcinoma

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab97272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/2000. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/500.

ターゲット情報

  • 機能
    Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
  • 組織特異性
    Abundant expression in the intestinal tract.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾
    Phosphorylated. FFA stimulation facilitates phosphorylation.
  • 細胞内局在
    Cell membrane. Colocalized with ARRB2 following DHA treatment.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BMIQ10 antibody
    • FFAR4 antibody
    • Free fatty acid receptor 4 antibody
    • G protein coupled receptor 120 antibody
    • G protein coupled receptor 129 antibody
    • G protein coupled receptor GT01 antibody
    • G protein coupled receptor PGR 4 antibody
    • G protein coupled receptor PGR4 antibody
    • G-protein coupled receptor 120 antibody
    • G-protein coupled receptor 129 antibody
    • G-protein coupled receptor GT01 antibody
    • G-protein coupled receptor PGR4 antibody
    • GPR 120 antibody
    • GPR 129 antibody
    • GPR120 antibody
    • GPR129 antibody
    • GT01 antibody
    • HGNC:19345 antibody
    • MGC119984 antibody
    • O3FA1_HUMAN antibody
    • O3FAR1 antibody
    • Omega-3 fatty acid receptor 1 antibody
    • PGR 4 antibody
    • PGR4 antibody
    see all

Anti-GPCR GPR120 antibody 画像

  • Anti-GPCR GPR120 antibody (ab97272) at 1/2000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 42 kDa
  • ab97272, at a 1/500 dilution, staining GPCR GPR120 in paraffin embedded Human prostate adenocarcinoma by Immunohistochemical analysis (20X magnification).
  • ab97272, at a 1/500 dilution, staining GPCR GPR120 in paraffin embedded Human prostate adenocarcinoma by Immunohistochemical analysis (40X magnification).

Anti-GPCR GPR120 antibody (ab97272) 使用論文

This product has been referenced in:
  • Yamada H  et al. Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice. Nutr Metab (Lond) 14:33 (2017). WB ; Mouse . Read more (PubMed: 28503189) »

See 1 Publication for this product

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Thank you for your inquiry.

The exact immunogen sequence is proprietary information and I also do not have access to it.

But I would like to confirm that I blasted the sequence of the amino acid range of 1 -41and found only one simi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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